Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor that grows in the back of the nasal cavity. It most commonly affects adolescent males and may grow into fissures of the. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. % represents % of head and. Angiofibroma nasofaring juvenile – Free download as PDF File .pdf), Text File . txt) or read online for free.

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Histopathologically JNA shows a fibrocellular stroma with spindle cells and haphazardly arranged collagen interspersed with an irregular vascular pattern. Treatment for Nasopharyngeal angiofibroma JNA is primarily surgical. Intraoral view showing swelling on the upper left side of the maxilla and obliteration of the vestibule. Sign up for our Email Newsletters. JNA is classified as Type I when the tumor is restricted to the nasal cavity and the nasopharynx without bone destruction, Type II when the tumor invades the pterygomaxillary fossa and maxillary, sphenoidal and ethmoid sinuses with bone destruction, Type III when the tumor invades the infratemporal fossa, the orbit, and the parasellar region but remains lateral to the cavernous sinus and Type IV when the tumor invades the cavernous sinus, the optic chiasma and the pituitary fossa.

The classification and clinical staging is relatively easy and helps to plan treatment and determine prognosis.

Juvenile nasopharyngeal angiofibroma

Continuous growth involves the sphenoidal sinus, nasal fossa and middle turbinate, pterygomaxillary fossa and the posterior wall of the maxillary sinus as seen in the present case. J Clin Imaging Sci.

Typically a lobulated non-encapsulated soft tissue mass is demonstrated centred on the sphenopalatine foramen which is often widened and usually bowing the posterior wall of the maxillary antrum anteriorly. Articles from Journal of Oral and Maxillofacial Pathology: Fisch classification, however, is currently accepted. Nasal cavity Esthesioneuroblastoma Nasopharynx Nasopharyngeal carcinoma Nasopharyngeal angiofibroma Larynx Laryngeal cancer Juvennile papillomatosis.


Tumour of the respiratory system. Home About Us Advertise Amazon. Relative distribution of the tumours of ear, nose and throat in the paediatric patients. This makes it possible to precisely stage JNA.

Click here for information on linking to angioribroma website or using our content or images. Conflicts of interest There are no conflicts of interest.

About Blog Go ad-free. Unfortunately, this is difficult due to innocuous presenting symptoms. It is an aggressive neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium. Findings are similar to those described above. Nasopharyngeal angiofibroma[TI] free full text[sb]. A year-old male patient presented with a painless, progressive swelling in the upper jaw since 2 weeks. Case 1 Case 1. At the time of diagnosis, the mass classically involves the pterygopalatine fossa.

This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. Biological distinctions between juvenile nasopharyngeal angiofibroma and vascular malformation: These techniques help to establish the exact site, extension and relation of the tumor to the adjacent structures such as blood vessels and nerves. The origin and development of JNA is not fully understood.

Type III is a calabash-like massive tumor lobe in the middle cranial fossa. MRI is superior to CT for detecting soft tissue extension of the tumor intracranially.

Computed tomography CT scan showed the presence of a soft tissue mass involving the maxillary sinus, nasal cavity, and nasopharynx. Extensive bony destruction is usually not a feature, but rather bone is remodelled or resorbed. Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma.

Nasopharyngeal angiofibroma

DSA digital subtraction angiography of carotid artery to see the extension of tumors and feeding vessels. A higher density toward the periphery is noted, which was seen in the present case naeofaring. CT images show a heterodense mass that is centered in the sphenopalatine foramen.


Biopsy should be avoided as to avoid extensive bleeding since the tumor is composed of blood vessels without a muscular coat.

This feature may be helpful is differentiating from other angiofibrooma aggressive lesions. A wait and watch policy with periodic imaging may thus postpone or eliminate the need for surgery and reduce morbidity. They account for only 0. Although these masses are thought to arise from the region of the sphenopalatine foramenthey are usually sizeable at diagnosis, frequently with extension medially into the nasopharynxlaterally into the pterygopalatine fossa and over time beyond, into the orbitparanasal sinusesintracranial cavity and infratemporal fossa.

Please review our privacy policy. Angiofibromas originating outside the nasopharynx may appear as an intraoral nasotaring in the retromolar or buccal space area.

Synonyms or Alternate Spellings: A case report of JNA with rare intra-oral manifestation in a year-old male patient is presented in the article. It is, as the name suggests, very vascular and a biopsy can sometimes be fatal. They develop at a slightly older age and occur more commonly in women. Type I includes lesions fundamentally localized to the nasal cavity, paranasal sinus, nasopharynx, or pterygopalatine fossa.

The main clinical presentation of JNA is unilateral nasal obstruction with or without epistaxis. Eventually, the tumor may invade the infratemporal fossa and the middle cranial fossa.

A typical staghorn type appearance is seen. Articles Cases Courses Quiz. Mesothelioma Malignant solitary fibrous tumor.